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8:04
YouTube
JJ Medicine
Introduction to RANKL | RANK | OPG Signaling Pathway
Lesson on the RANKL / RANK / OPG Signaling Pathway: Purpose and Mechanism. The RANKL-RANK-OPG Signaling pathway is an important pathway in bone remodelling and is important in various osteopathies such as osteoporosis. Osteoblasts are bone forming cells, which express and release the protein RANK ligand (RANKL) and osteoprotegerin (OPG). RANK ...
108.1K views
Jul 17, 2018
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RANKL and Osteoporosis
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Video: A RANKL-based Osteoclast Culture Assay of Mouse Bone Marrow to Investigate the Role of mTORC1 in Osteoclast Formation
jove.com
14K views
Mar 15, 2018
0:40
DEXAMETASONA PARA TODO Los glucocorticoides favorecen la osteoporosis a través de múltiples mecanismos que afectan tanto la formación como la resorción ósea. En primer lugar, inducen apoptosis y disminuyen la proliferación de osteoblastos y osteocitos, lo que reduce la formación de hueso nuevo y compromete la capacidad de mantenimiento y reparación ósea.[1][2][3][4] Además, los glucocorticoides aumentan la expresión de RANKL y disminuyen la de osteoprotegerina (OPG), lo que promueve la diferenci
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