ulatory sequences of Col2a1 (Murakami et al., 2004). In this review, we will summarize the roles of the ERK MAPK pathway in skeletal development based on our rece st dies using genetically engineered …

This review offers a comprehensive analysis of MAPK/ERK signaling pathway, focusing on its molecular components and its contribution to RA pathophysiology.

These findings suggest that the ERK signaling pathway plays an important role in prolonged orthodontic treatment-induced pain via the transcriptional regulation of pain-related genes by Fos.

The crosstalk between the ERK signaling pathway and other cellular signaling pathways that control Schwann cell myelination is discussed. Finally, the roles of the ERK signaling pathway in developing …

Here, we focus on recent findings on the convergent regulation of downstream functions by AKT and ERK pathways and discuss the biologic and therapeutic relevance of the pathway convergence in …

The extracellular signal-regulated kinase (ERK) signaling pathway is a major determinant in the control of diverse cellular processes such as proliferation, survival, differentiation and motility.

They review the literature investigating the effects of ERK1/2 signaling in the renal tubule in mature kidneys and discuss the molecular mechanisms by which ERK1/2 regulates the function of several …