BRAF is a human gene that encodes a protein called B-Raf. The gene is also referred to as proto-oncogene B-Raf and v-Raf murine sarcoma viral oncogene homolog B, while the protein is more …

The BRAF gene provides instructions to a protein responsible for managing important cell functions related to growth. If there is a mutation in the gene, it stops working correctly and signals cells to …

The BRAF gene provides instructions for making a protein that helps transmit chemical signals from outside the cell to the cell's nucleus. Learn about this gene and related health conditions.

Apr 16, 2024 · In this review, we cover the current understanding of BRAF mutations and associated clinical characteristics in patients with metastatic NSCLC, approved and emerging treatment options, …

Sep 15, 2025 · BRAF mutations are present in many melanomas as well as some lung cancers, colon cancers, and more. Learn about the basics, testing, and treatment.

Nov 13, 2025 · BRAF (B-Raf Proto-Oncogene, Serine/Threonine Kinase) is a Protein Coding gene. Diseases associated with BRAF include Lung Cancer and Cardiofaciocutaneous Syndrome 1. …

5 days ago · The BRAF gene and its corresponding protein are central to cancer research and treatment today. The gene belongs to a class of proto-oncogenes, which are involved in cell growth and …

With the identification of activating mutations in BRAF across a wide variety of malignancies, substantial effort was placed in designing safe and effective therapeutic strategies to target BRAF.

2 days ago · Targeted inhibition of mutant BRAF has transformed the management of BRAF-V600–mutant melanoma and other malignancies, with multiple ATP-competitive kinase inhibitors …

4 days ago · The PHAROS trial supports Braftovi and Mektovi for BRAF V600E-mutant non-small cell lung cancer, showing improved survival and tolerability in treatment-naive patients. Comprehensive …