Copyright held by the owner/author(s). This open access article is distributed under the Creative Commons Attribution 4.0 International (CC BY 4.0) license.
Copyright held by the owner/author(s). This open access article is distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International ...
Major Finding: FastGlioma, an AI-based visual model, rapidly scores the degree of glioma infiltration in surgical samples. Concept: This approach represents a rapid, label-free surgical adjunct that ...
Copyright held by the owner/author(s).
Treatment with eflornithine led to clinically meaningful improvements in overall survival (OS) and progression-free survival (PFS) for patients with recurrent grade 3 IDH-mutant astrocytoma, an ...
1Fred Hutchinson Cancer Center, Seattle, WA.
Major Finding: A dual function supracluster was engineered to increase radiosensitivity and antitumor immunity. Concept: Gold supraclusters carrying siRNA against LGALS1 (galectin-1) reshaped the ...
Chimeric antigen receptors (CAR) enable MHC-independence but do not recreate the precise molecular regulation induced by T-cell receptor (TCR) complexes. In an effort to engage endogenous TCR circuits ...
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Bristol Myers Squibb (BMS) faces a $6.7 billion lawsuit alleging that the company purposely delayed approval of Celgene-developed drugs to avoid paying Celgene shareholders owning contingent value ...
Background: Although cancer associated fibroblast (CAF) heterogeneity is recognized in oral squamous cell carcinoma (OSCC), the phenotype and role of CAF subpopulations in OSCC is still unknown.
Dive into how members of the Cukierman lab and their collaborators explore desmoplasia, the dense “shield” around tumors. Discover their groundbreaking 3D model that reveals the intricate “symphony” ...
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