San Francisco 49ers coach Kyle Shanahan is sharing an update on Trent Williams and his family after the left tackle's son was ...

San Francisco 49ers defensive back Deommodore Lenoir shares a heartfelt tribute to his sister and loved ones with Down ...

The San Francisco 49ers and fantasy football players who were relying on the NFC West team's running backs are probably all ...

The San Francisco 49ers’ 35-10 Week 13 loss to the Buffalo Bills was costly in more ways than one. Not only did it make San ...

Vinnie Iyer is back for another week of season-long fantasy football lineup advice, bringing his rankings and insights across ...

This Sunday, the 49ers will wear their customized cleats on the field to amplify the causes close to their hearts off the ...

Ricky Pearsall Jr., the 49ers first-round draft pick, was shot through the chest on Aug. 31 in a robbery attempt.

The 49ers signed two running backs to their practice squad after Christian McCaffrey and Jordan Mason were placed on injured ...

The San Francisco 49ers have signed a former New York Jets running back to replace the injured Christian McCaffrey and Jordan ...

After spending more than $2 million on four Santa Clara City Council races, the San Francisco 49ers saw three of the four ...

Even if it’s the longest of longshots, the mere air that Kyle Shanahan leaving San Fran exists in whisks him into our ...

Rookie Isaac Guerendo steps up as 49ers seek to fill void left by McCaffrey and injured backup Jordan Mason. Coach Shanahan ...