The San Francisco 49ers may soon lose one of their best offensive players to the Minnesota Vikings in free agency.

ORCHARD PARK, NEW YORK – DECEMBER 01: Mack Hollins #13 of the Buffalo Bills celebrates after scoring a touchdown in the ...

Event details about Buffalo Bills vs San Francisco 49ers Live Stream: Watch NFL Football Week 13 p2p Online Free Video ...

Add in All Leagues ROSTERED IN: 5% of Yahoo Leagues ANALYSIS: San Francisco 49ers running back Isaac Guerendo is the RB63 for ...

San Francisco 49ers coach Kyle Shanahan is sharing an update on Trent Williams and his family after the left tackle's son was ...

How to watch Sunday's Bears and 49ers game with betting trends and radio information as Caleb Williams and Co. try to win ...

Former Wisconsin Badgers running back Isaac Guerendo is in line to serve as the San Francisco 49ers starting running back for ...

The San Francisco 49ers' season has been on the brink for weeks, and the Week 13 blowout loss to the Buffalo Bills certainly ...

The plan appears to be a heavy dose of Guerendo with the only other halfbacks on the roster being Patrick Taylor, who has 72 ...

NFL Week 14 odds, picks, predictions, TV channel, streaming information for Sunday football game between Chicago Bears and ...

The Bills are a Super Bowl contender and the 49ers somehow probably aren’t even a playoff team. That’s how Sunday night’s ...

Head coach Kyle Shananhan said running back Christian McCaffrey suffered a knee injury during the team's 35-10 loss to the ...