Notre Dame will always be compared to USC as USC will always be compared to Notre Dame. That's just how rivalries have always gone and will always go. The matchup between the two happens on Thanksgiving weekend this year and could be huge in determining College Football Playoff bids.

That doesn’t matter much across the college football landscape, as Week 4 is set to take place. The Fighting Irish Wire crew of Geoffrey Clark, Tim Healey and Michael Chen pick the winner of the top games of the week along with Notre Dame against Miami (OH).

Notre Dame hosts Miami (Ohio) on Saturday in South Bend, and though it represents just the third meeting of the two programs, these two prestigious Midwestern universities have some notable ties off the field.