Ever since making the switch from high school receiver to running back in college, Isaac Guerendo has had few opportunities ...

Christian McCaffrey on Wednesday shared his first message to his fans after suffering a season-ending injury on Sunday.

Running back Christian McCaffrey is on injured reserve for the second time this season, but San Francisco 49ers coach Kyle ...

Christian McCaffrey's injury-ridden season took another unfortunate turn when the star running back went down with another ...

McCaffrey immediately checked himself out of the game and ran right into the medical tent. The 49ers star RB missed the ...

San Francisco 49ers running back Christian McCaffrey reflected on his 2024 NFL season that fell short of expectations with a ...

Isaac Guerendo didn’t start in college until his final game.. He starts at running back for the 49ers Sunday against Chicago.

McCaffrey appeared to have finally gotten untracked against ... and Guerendo became the lead runner for a team that is sixth ...

On Wednesday, McCaffrey, the former Carolina Panthers star, shared his initial thoughts on the 2024 NFL season following his ...

McCaffrey's post garnered all sorts of reactions from fans and NFL personalities alike. One that stood out, however, is his wife Olivia Culpo's five-word message for her husband, who is clearly going ...

Isaac Guerendo will make his first NFL start on Sunday as the injury-depleted San Francisco 49ers face the Chicago Bears. The ...

Slow motion video shows where 49ers running back Christian McCaffrey seemingly injured himself and ended his season.