Back-to-back blowout losses and another injury to star back Christian McCaffrey might just be the final blow to the dwindling ...

SANTA CLARA, CALIFORNIA - JANUARY 22: Christian McCaffrey #23 of the San Francisco 49ers rushes for a touchdown against the ...

The San Francisco 49ers' season has been on the brink for weeks, and the Week 13 blowout loss to the Buffalo Bills certainly ...

Sondra Williams, the wife of San Francisco 49ers left tackle Trent Williams, announced Monday that the couple had a son, ...

The Detroit Lions won't face Christian McCaffrey in Week 17 this season. The San Francisco 49ers running back injured the PCL ...

The San Francisco 49ers were hit by another family tragedy with the announcement that star left tackle Trent Williams’ wife ...

San Francisco 49ers star running back Christian McCaffrey will not need surgery on his injured right knee but he will miss ...

The San Francisco 49ers entered this season with lofty aspirations. For the most part, their hopes have been dashed -- and ...

The San Francisco 49ers’ dreadful season got worse in Week 13 when running backs Christian McCaffrey and Jordan Mason both ...

San Francisco 49ers star left tackle Trent Williams’ newborn son passed away last week, his wife Sondra announced on ...

Head coach Kyle Shanahan shared the latest injury and team updates emerging from the San Francisco 49ers Week 13 matchup ...

Hall of Fame wide receiver Randy Moss revealed he’s dealing with a health issue and asked fans to pray for him and his family ...