San Francisco 49ers defensive end Nick Bosa missed Wednesday's practice as the team began preparations for Sunday's game ...

The San Francisco 49ers will be missing two of their best players in their must-win matchup against the Green Bay Packers ...

The San Francisco 49ers will be without their starting quarterback and their best defensive player when they visit the Green ...

Bosa (hip/oblique) will not practice Wednesday, Nick Wagoner of ESPN.com reports. Bosa missed last Sunday's loss to the Packers after he was injured in the Week 11 loss to the Seahawks. Sam Okuayinonu ...

This just isn't the 49ers' week. They have now been dealt the worst-case scenario with Nick Bosa's status against the Packers ...

San Francisco 49ers head coach Kyle Shanahan has offered an update on the injuries to Nick Bosa and Brock Purdy.

Kyle Shanahan made a stunning revelation involving the health of Nick Bosa following the loss to the Seahawks.

The San Francisco 49ers are expecting to get star tight end George Kittle back this week for a key game against Green Bay, ...

San Francisco 49ers tight end George Kittle confidently declared on Wednesday that he will suit up for this weekend's game ...

The San Francisco 49ers fell to 5-6 on the season in losing to the Green Bay Packers on Sunday. Top takeaways with Brock ...

The San Francisco 49ers got a taste of what their defense looks like without Nick Bosa in the second half of a loss to the ...

Jaire Alexander, Edgerrin Cooper, Brock Purdy and Nick Bosa were all ruled out Friday; 49ers LT Trent Williams joins them on ...