The San Francisco 49ers (5-6) try to salvage their season against the Buffalo Bills (9-2) on Sunday Night Football. Kickoff from Highmark Stadium is set for 8:20 p.m. ET (NBC). Let's analyze BetM

Evan Reier is a sports journalist covering the NFL for Heavy.com, with a focus on the Dallas Cowboys and San Francisco 49ers. He previously covered sports for the Montana Standard and was a managing editor for Outsider. More about Evan Reier

After that, there is no significant NFL talent on the 49ers roster, while the edges are equally deficient in both depth and run-stopping abilities. For that reason, the Bills may pursue interior runs early and often while San Francisco struggles to find ...

SportsLine's model has simulated San Francisco vs. Buffalo on Sunday Night Football 10,000 times and revealed its SNF picks and NFL predictions

The San Francisco 49ers and Buffalo Bills are set to face-off in the Week 13 edition of Sunday Night Football. Before the season began, this matchup was circled

Dive into the San Francisco 49ers vs. Buffalo Bills showdown with a look at odds, predictions, and the best betting options.

Under head coach Kyle Shanahan, the San Francisco 49ers have spent years falling just inches short of the franchise’s sixth Lombardi Trophy. The Niners have mad

Player prop bets will be available for Josh Allen ahead of Sunday’s NFL action at 8:20 PM ET live on NBC. The Buffalo Bills (9-2) and Allen face off versus the San Francisco 49ers (5-6) in a

The Buffalo Bills (9-2) enter a matchup with the San Francisco 49ers (5-6) on Sunday, December 1, 2024 at Highmark Stadium on a

Star pass-catcher George Kittle and the San Francisco 49ers meet the Buffalo Bills on Sunday at 8:20 p.m. ET at Highmark Stadium.The Bills sport the seventh-ranked defense this season (19.5 points

"Sunday Night Football" in Week 13 sees the San Francisco 49ers taking on the Buffalo Bills. Here's the latest on a snowy forecast for the game.