They don't get a divisional opponent in Week 13, but a struggling San Francisco 49ers team still possesses plenty of firepower for Buffalo to be concerned with as it starts December. Here are five ...

Indianapolis Colts (5-7) at New England Patriots (3-9), 8 a.m. HST, CBS ...

San Francisco 49ers quarterback Brock Purdy is poised to return to action on Sunday night against the Buffalo Bills after ...

Brock Purdy will make his return from a shoulder injury this Sunday when the 49ers face the Buffalo Bills. On Friday, Purdy ...

There are no teams on bye around the NFL in Week 13, which means we'll be treated to a packed slate of Sunday games even ...

San Francisco 49ers star quarterback Brock Purdy has been given an injury update in time for their Week 13 match up against ...

Lawrence, who is listed as questionable, has missed the past two Jaguars games due to a sprained left shoulder suffered on ...

Check out the top 10 catches from San Francisco 49ers tight end George Kittle from his eight year career, so far.

One thing does not change, though. The defending NFC champion 49ers are 5-6 and they need to get on a heater - which will be ...

The Buffalo Bills (9-2) bring a six-game winning streak into a matchup with the San Francisco 49ers (5-6) on Sunday, December 1, ...

Sam Darnold is “excited” about Daniel Jones’ next NFL chapter in Minnesota. On Wednesday, the same day it was reported the ...

Buffalo (9-2) has won six straight games and is on the verge of a fifth consecutive AFC East crown. The Miami Dolphins (5-7) ...