Moderate expression of CD39 in GPC3-CAR-T cells shows high efficacy against hepatocellular carcinoma
In the quest to enhance the efficacy of chimeric antigen receptor T (CAR-T) cell therapy against hepatocellular carcinoma (HCC), a study in Frontiers of Medicine has identified a pivotal role for CD39 ...
Gut microbes play key role in regulating stress responsiveness throughout the day, research finds
A pioneering study has uncovered the vital role that gut microbiota plays in regulating stress responses by interacting with ...
Two genes linked to rheumatoid arthritis and osteoporosis could serve as targets for diagnosis and treatment
Rheumatoid arthritis is a common disease affecting an estimated 17 million people worldwide. The disease is caused by immune cells attacking the joints and can result in pain, swelling, and damage to ...
Alzheimer's and alcohol use disorder found to share similar gene expression patterns
Nearly 7 million Americans have Alzheimer's disease, and this number is predicted to double by 2060. While aging and genetic predisposition are the most important risk factors for Alzheimer's, ...
Study explores effective strategies to combat loneliness in older adults
Loneliness among older adults is a growing public health concern, linked to cardiovascular disease, substance abuse, mental ...
Meal timing may be crucial for night shift workers' health, study reveals
An Australian study published in Diabetologia has found that overnight eating may be putting night shift workers at higher ...
'Foam cells' that accelerate tumor growth in glioblastoma can be inhibited, researchers discover
A research team at Lund University in Sweden has discovered a certain type of cell—foam cells—in patients with the aggressive ...
Black Americans still suffer worse health: Why there's so little progress
One morning in late April, a small brick health clinic along the Thurgood Marshall Highway bustled with patients.
The chaotic beginnings of the tool that made heart surgery possible
Over the past century, heart operations that once were unthinkable have become commonplace. Thousands of times a day, ...
Study finds pandemic contribution from voluntary sector is 'under-valued'
A study has found that the voluntary, community, faith and social enterprise (VCFSE) sector played a "crucial" role ...
Researchers reveal the long, silent history of sports concussion
University of Queensland researchers have uncovered the hidden history of concussion in sport, finding the brain-trauma ...
Experts suggest Michelangelo depicted breast cancer in the Sistine Chapel fresco
Led by forensic pathologist Andreas G. Nerlich of Ludwig-Maximilians-University in Munich, a team of international experts propose that Michelangelo's fresco "The Flood" in the Sistine Chapel portrays ...