San Francisco 49ers quarterback Brock Purdy is still making quite an impact in the state of Iowa despite being three years ...

George Kittle could have to miss his first game of the season as the San Francisco 49ers take on the Los Angeles Rams on ...

The offense looked like it misses Christian McCaffrey but the defense was surprisingly exposed. Now that Deebo Samuel is hurt ...

NFL Week 3 odds, picks, predictions, TV and streaming information for the Sunday football game between the San Francisco ...

The Minnesota Vikings and the San Francisco 49ers square off today in a NFL Week 2 showdown. Find out how to watch.

ET/10 a.m. PT The San Francisco 49ers will visit the Minnesota Vikings this Sunday, Sept. 15, airing live at 1 p.m. ET on CBS ...

In June, Jefferson signed a record-setting deal with Minnesota. The four-year, $140 million contract extension made Jefferson ...

San Francisco 49ers left tackle Trent Williams said he wants to play until he's 40 years old, per NFL on CBS. More News: Jets ...

Do we have a revenge game on our hands in NFL Week 2? Sam Darnold – the San Francisco 49ers backup quarterback last season – ...

The 49ers and Vikings had two of the Top 5 most impressive wins during Week 1 of the NFL season, but only one can come away 2 ...

Sam Darnold passed for 268 yards and two touchdowns against his former team, including a 97-yard strike in the second quarter ...

Both the Vikings and 49ers dominated their Week 1 opponents. Only one can leave Week 2 still undefeated, and only limited ...