Medscape1mon
TNF Signaling Inhibition in the CNS: Implications for Normal Brain Function and Neurodegenerative Disease
thalidomide which enhances degradation of TNF mRNA, and TACE inhibitors which prevent TACE induced release of solTNF.
Nature10mon
Real-time quantitative RT–PCR after laser-assisted cell picking
Tumor necrosis factor-α (TNF-α) mRNA served as the target gene and is known to be substantially upregulated in macrophages in response to inflammatory agents like lipopolysaccharide (LPS ...
eLife9d
Increased bone inflammation in type 2 diabetes and obesity correlates with Wnt signaling downregulation and reduced bone strength
Type 2 diabetes (T2D) and obesity (OB) are associated with chronic low-grade inflammation and increased fracture risk. In vitro studies showed that inflammation induces bone erosion and inhibits bone ...