NFL fans are in for a remarkable showdown on Sunday night when the San Francisco 49ers travel to Highmark Stadium to take on the Buffalo Bills in a crucial matchup. However, the 49ers may face more than just a tough opponent — they're up against some truly unprecedented weather.

It’s that time of year again in Western New York. The Buffalo metro area is bracing for heavy lake-effect snowfall leading up to kickoff between the Bills (9-2) and 49ers (5-6) on “Sunday Night Football.

One thing does not change, though. The defending NFC champion 49ers are 5-6 and they need to get on a heater - which will be tough to do Sunday night in Buffalo - if they stand any chance of defending their crown because right now they’re in last place in the NFC West and sitting outside the NFC wild-card picture.