Running back Christian McCaffrey says the 49ers are “hungry” to make a playoff push even with the defending NFC champions ...

The Buffalo Bills will look to clinch the AFC East on Sunday with a win against the San Francisco 49ers in what's expected to ...

The Buffalo Bills have activated Matt Milano from injured reserve, putting the starting linebacker in position to play Sunday ...

The west coast based team is in for a lot of snow in Week 13 when they head to Orchard Park to face the Bills (9-2). The ...

The Buffalo Bills will host the San Francisco 49ers at Highmark Stadium on “Sunday Night Football ... Tight end George Kittle ...

The San Francisco 49ers (5-6) try to salvage their season against the Buffalo Bills (9-2) on Sunday Night Football. Kickoff ...

The deal is pretty simple: The Bills will pay $20 per hour and provide food, hot beverages and shovels to those who sign up.

Defensively, two of the 49ers’ best players this season are out and will not travel as defensive end Nick Bosa (obliques, ...

The San Francisco 49ers have released their final injury report ahead of their Week 13 bout with the Buffalo Bills.

The Packers boast an 8-3 record heading into their Thanksgiving Day showdown against the Dolphins but that's only good for ...

You can listen on SiriusXM satellite radio on channel 225 (Bills feed) and channel 226 (49ers feed), and on traditional radio ...

The Jets are back in action following a bye week. Can Gang Green get back in the win column? Here are our staff predictions ...