The high-resolution structure of full-length Pin1 complexed to the C-terminal tail of PKCβII reveals that a novel bivalent interaction mode underlies the non-catalytic mode of Pin1 action.
Today, a cast-iron wood-burning stove reads as old-fashioned ... There’s also two basic technological types: catalytic and non-catalytic. Without getting too deep into the weeds, catalytic stoves are ...
By analyzing the single-molecule properties of engineered motors, we demonstrate that the non-catalytic domain has a key role in the motility mechanism by acting as a ‘foothold’ that allows Kar3 to ...