The EMBO Journal6d
PDE12 mediated pruning of the poly-A tail of mitochondrial DNA-encoded tRNAs is essential for survival
Mitochondrial DNA (mtDNA)-encoded RNA molecules undergo extensive processing to generate mature RNA, including removal of ...
The EMBO Journal1d
New players and targets in mannose 6-phosphate-dependent lysosomal sorting
Amidst the wide variety of glycan modifications that are carried out in the Golgi apparatus, the addition of mannose 6-phosphate (M6P) to the N-linked glycans of lysosome-resident hydrolase enzymes ...
The EMBO Journal6d
Soul Men and Women—what must science do to regain public trust?
Whether it amounts to anything in the very long run, preserving this planet and its occupants safely for the next hundred ...
The EMBO Journal3d
KMT5C leverages disorder to optimize cooperation with HP1 for heterochromatin retention
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. A defining feature of constitutive ...
The EMBO Journal5d
Interleukin-2-mediated NF-κB-dependent mRNA splicing modulates interferon gamma protein production
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. IL-2 stimulation post-transcriptionally ...
The EMBO Journal5d
The DNA demethylase TET1 modifies the impact of maternal folic acid status on embryonic brain development
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Interactions between modified maternal folic ...
The EMBO Journal7d
Melanin-like nanoparticles slow cyst growth in ADPKD by dual inhibition of oxidative stress and CREB
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Melanin-like nanoparticles (MNPs) have ...
The EMBO Journal5d
Structural insight into Okazaki fragment maturation mediated by PCNA-bound FEN1 and RNaseH2
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. PCNA is a master coordinator of many ...
The EMBO Journal8d
ZBTB48 is a priming factor regulating B-cell-specific CIITA expression
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The class-II transactivator (CIITA) is the ...
The EMBO Journal6d
Sex-specific regulatory architecture of pancreatic islets from subjects with and without type 2 diabetes
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Patients with type 2 and type 1 diabetes (T2D ...