Rookie wide receiver Ricky Pearsall exploded in Week 10 against the Tampa Bay Buccaneers. He was targeted seven times, ...

Christian McCaffrey's injury-ridden season took another unfortunate turn when the star running back went down with another ...

Former Wisconsin Badgers running back Isaac Guerendo is in line to serve as the San Francisco 49ers starting running back for ...

The San Francisco 49ers may soon lose one of their best offensive players to the Minnesota Vikings in free agency.

San Francisco 49ers coach Kyle Shanahan is sharing an update on Trent Williams and his family after the left tackle's son was ...

Star pass-catcher George Kittle and the San Francisco 49ers play the Buffalo Bills on Sunday at 8:20 p.m. ET at Highmark ...

San Francisco 49ers' Trent Williams' wife Sondra has announced the death of their baby son at 35 weeks after losing his twin ...

Williams’ wife, Sondra, announced on Instagram on Sunday, Dec. 1 that their son Trenton O'Brien Williams Jr. was stillborn on ...

Add in All Leagues ROSTERED IN: 5% of Yahoo Leagues ANALYSIS: San Francisco 49ers running back Isaac Guerendo is the RB63 for ...

San Francisco 49ers star running back Christian McCaffrey will not need surgery on his injured right knee but will miss the ...

Sondra Williams, the wife of San Francisco 49ers pro offensive tackle Trent Williams, announced the tragic death of their ...

It's Buffalo Bills vs San Francisco 49ers in Week 13 of the NFL season. Can Josh Allen and company outduel Christian ...