We spoke to our expert Dr Balakrishna GK, Senior Consultant - Internal Medicine, Gleneagles BGS Hospital, Kengeri, Bengaluru, who explained how TNF functions and its impact on the body.

Anti-tumor necrosis factor (TNF) therapy for new-onset inflammatory bowel disease (IBD) was independently associated with progressive kidney function decline but not survival, a VA cohort study found.

New research shows that blockade of tumor necrosis factor (TNF) leads to impaired dendritic cell survival and function, and provides insight into why TNF antagonists are effective treatments for ...

Cite this: TNF Signaling Inhibition in the CNS: Implications for Normal Brain Function and Neurodegenerative Disease - Medscape - Oct 17, 2008.

In fact, the only actions then associated with TNF were the tumor-necrotizing activity in animals, cytotoxic action in some tumor cell lines and the postulated function of cachectin (now known to ...

The findings suggest that TNF, long considered a key galvanizer of the immune response, might actually play a much narrower ...

Cite this: TNF Signaling Inhibition in the CNS: Implications for Normal Brain Function and Neurodegenerative Disease - Medscape - Oct 17, 2008. Schematic of TNF inhibitors and their mode of action.