Dihydropteroate synthase (DHPS) is a crucial enzyme in the folate biosynthetic pathway, catalysing the formation of essential folate cofactors that underpin DNA synthesis and cellular functioning.
Tilting the scales at 4.7 megadaltons and reaching 1 micron in length, the newly discovered algal enzyme PKZILLA-1 is the largest protein ever identified in biology. Indeed, PKZILLA-1 is 25% larger ...
Marine algae Prymnesium parvum use massive enzymes dubbed PKZILLAs – some of the largest proteins ever to be identified in nature – to make large and complex prymnesin neurotoxins responsible for mass ...
A bacterium has evolved an enzyme that assembles in a fractal structure, a mathematical pattern that repeats itself at smaller scales. Fractal patterns are found throughout nature on large, ...
Mineralys Therapeutics enjoyed a big stock bump after its aldosterone synthase inhibitor chalked up wins in two types of hypertension. The therapy, called lorundrostat, hit the primary endpoint of the ...
Dual role of p21waf1/cip1 in effects of oxaliplatin (L-OHP) against colon cancer cells in p53 dependent and independent pathway ...
Researchers at Martin Luther University Halle-Wittenberg (MLU) have developed a promising new substance for targeting bacteria that cause tuberculosis. The team have produced a compound that inhibits ...
Mineralys Therapeutics’ aldosterone synthase inhibitor has chalked up a third clinical win in recent months, demonstrating once again its potential to reduce blood pressure in patients with ...
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Andrew O’Donnell in front of a gel imaging system. The gel image visualizes the purified ancestral terpene synthase enzymes examined in the study. Conifers, such as pines, spruces, and firs, produce ...
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