Barring a sudden physical setback, San Francisco running back Christian McCaffrey will make his season debut on Sunday against Tampa Bay. So those folks who drafted him with the No. 1 pick will

Fantasy point totals are PPR. Roster percentages are per ESPN leagues. Unless otherwise noted, statistical rankings are through the Sunday night games. Forget the final point total Dak Prescott posted versus the San Francisco 49ers Sunday night.

To help you make the best calls when setting your NFL fantasy lineup in Week 10, we have flex rankings available for you below. Take a look before kickoff. Underdog Fantasy is the best place to play fantasy sports including Best Ball, Daily Drafts and Pick'em. Use our link to start drafting in minutes.

Just an average smash output in Week 9. Matthew Stafford, Chuba Hubbard, Darnell Mooney and the Tennesse Titans’ defense gave fantasy managers smash plays that provided the edge they needed to win in their Week 9 matchups.

We're heading into Week 10 of the NFL, and have just a little over a month left in the regular season in most fantasy leagues. For Week 10, the Cleveland Browns, Green Bay Packers, Las Vegas Raiders and Seattle Seahawks will rest their collective bumps and bruises.