Ludlow is a home rule-class city in Kenton County, Kentucky, United States, along the Ohio River. The population was 4,385 at the 2020 c…Ludlow is a home rule-class city in Kenton County, Kentucky, United States, along the Ohio River. The population was 4,385 at the 2020 census. It is a suburb of the Cincinnati metropolitan area. It received its greatest period of early growth as a rail station.